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Distinct Signalling Pathways of Murine Histamine H(1)- and H(4)-Receptors Expressed at Comparable Levels in HEK293 Cells
Histamine (HA) is recognized by its target cells via four G-protein-coupled receptors, referred to as histamine H(1)-receptor (H(1)R), H(2)R, H(3)R, and H(4)R. Both H(1)R and H(4)R exert pro-inflammatory functions. However, their signal transduction pathways have never been analyzed in a directly co...
Autores principales: | Beermann, Silke, Vauth, Marcus, Hein, Rabea, Seifert, Roland, Neumann, Detlef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171377/ https://www.ncbi.nlm.nih.gov/pubmed/25243776 http://dx.doi.org/10.1371/journal.pone.0107481 |
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