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Family-Based Association Test Using Both Common and Rare Variants and Accounting for Directions of Effects for Sequencing Data
Current family-based association tests for sequencing data were mainly developed for identifying rare variants associated with a complex disease. As the disease can be influenced by the joint effects of common and rare variants, common variants with modest effects may not be identified by the method...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171487/ https://www.ncbi.nlm.nih.gov/pubmed/25244564 http://dx.doi.org/10.1371/journal.pone.0107800 |