Cargando…

Chemotherapy Enhances Cross-Presentation of Nuclear Tumor Antigens

Cross-presentation of tumor antigen is essential for efficient priming of naïve CD8(+) T lymphocytes and induction of effective anti-tumor immunity. We hypothesized that the subcellular location of a tumor antigen could affect the efficiency of cross-presentation, and hence the outcome of anti-tumor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anyaegbu, Chidozie C., Lake, Richard A., Heel, Kathy, Robinson, Bruce W., Fisher, Scott A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171494/ https://www.ncbi.nlm.nih.gov/pubmed/25243472 http://dx.doi.org/10.1371/journal.pone.0107894

Ejemplares similares

Tumor cells, rather than dendritic cells, deliver antigen to the lymph node for cross-presentation
por: McDonnell, Alison M., et al.
Publicado: (2012)

Loss of antigen cross-presentation after complete tumor resection is associated with the generation of protective tumor-specific CD8(+) T-cell immunity
por: Brown, Matthew D., et al.
Publicado: (2012)

Restoration of defective cross-presentation in tumors by gemcitabine
por: McDonnell, Alison M, et al.
Publicado: (2015)

Tumor Antigen Cross-Presentation and the Dendritic Cell: Where it All Begins?
por: McDonnell, Alison M., et al.
Publicado: (2010)

TLR2 and TLR4 in Parkinson’s disease pathogenesis: the environment takes a toll on the gut
por: Gorecki, Anastazja M., et al.
Publicado: (2021)

Neoadjuvant anti-tumor vaccination prior to surgery enhances survival
por: Fisher, Scott A, et al.
Publicado: (2014)

Cancer chemotherapy: insights into cellular and tumor microenvironmental mechanisms of action
por: Tilsed, Caitlin M., et al.
Publicado: (2022)

Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis
por: Robinson, Cleo, et al.
Publicado: (2001)

PD‐L1+ dendritic cells in the tumor microenvironment correlate with good prognosis and CD8+ T cell infiltration in colon cancer
por: Miller, Timothy J., et al.
Publicado: (2021)

Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8(+) T Cell Tolerance Development
por: Damo, Martina, et al.
Publicado: (2021)

Synergistic Effect of CTLA-4 Blockade and Cancer Chemotherapy in the Induction of Anti-Tumor Immunity
por: Lesterhuis, W. Joost, et al.
Publicado: (2013)

Tumour-infiltrating regulatory T cell density before neoadjuvant chemoradiotherapy for rectal cancer does not predict treatment response
por: McCoy, Melanie J., et al.
Publicado: (2017)

Autophagy-assisted antigen cross-presentation: Autophagosome as the argo of shared tumor-specific antigens and DAMPs
por: Yi, Yongxiang, et al.
Publicado: (2012)

Localized, time-dependent responses of rat cranial bone to repeated mild traumatic brain injuries
por: Dill, Larissa K., et al.
Publicado: (2022)

The “Trojan Horse” Approach to Tumor Immunotherapy: Targeting the Tumor Microenvironment
por: Nelson, Delia, et al.
Publicado: (2014)

Chimeric Antigen Receptor-Engineered Human Gamma Delta T Cells: Enhanced Cytotoxicity with Retention of Cross Presentation
por: Capsomidis, Anna, et al.
Publicado: (2018)

International workshop on immune assay of nuclear antigens relevant to carcinogenesis and chemotherapy
Publicado: (1982)

Antigen Cross-Presentation by Macrophages
por: Muntjewerff, Elke M., et al.
Publicado: (2020)

Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen
por: Saluja, Sandeep S, et al.
Publicado: (2014)

MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas
por: Stopfer, Lauren E., et al.
Publicado: (2022)

A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice
por: Aston, Wayne J., et al.
Publicado: (2017)

CD206(+) tumor-associated macrophages cross-present tumor antigen and drive antitumor immunity
por: Modak, Madhura, et al.
Publicado: (2022)

Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer
por: Lu, Zhen, et al.
Publicado: (2022)

Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters
por: McDonnell, Alison M., et al.
Publicado: (2017)

Cyclophosphamide Chemotherapy Sensitizes Tumor Cells to TRAIL-Dependent CD8 T Cell-Mediated Immune Attack Resulting in Suppression of Tumor Growth
por: van der Most, Robbert G., et al.
Publicado: (2009)

Antigen Cross-Presentation of Immune Complexes
por: Platzer, Barbara, et al.
Publicado: (2014)

Sec61 in antigen cross-presentation
por: Zehner, Matthias, et al.
Publicado: (2015)

Current Concepts of Antigen Cross-Presentation
por: Embgenbroich, Maria, et al.
Publicado: (2018)

Cannabinoids in traumatic brain injury and related neuropathologies: preclinical and clinical research on endogenous, plant-derived, and synthetic compounds
por: Lins, Brittney R., et al.
Publicado: (2023)

Monitoring the responsiveness of T and antigen presenting cell compartments in breast cancer patients is useful to predict clinical tumor response to neoadjuvant chemotherapy
por: Bernal-Estévez, David A., et al.
Publicado: (2018)

Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines
por: García-Vallejo, Juan J., et al.
Publicado: (2013)

Polymer nanoparticles for cross-presentation of exogenous antigens and enhanced cytotoxic T-lymphocyte immune response
por: Song, Chanyoung, et al.
Publicado: (2016)

The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation
por: Reiser, Michael L., et al.
Publicado: (2017)

Site-specific mutagenesis of Drosophila proliferating cell nuclear antigen enhances its effects on calf thymus DNA polymerase δ
por: Mozzherin, Dmitry Ju, et al.
Publicado: (2004)

The Prognostic and Predictive Value of SOX2(+) Cell Densities in Patients Treated for Colorectal Cancer
por: Miller, Tim J., et al.
Publicado: (2020)

Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells
por: Jiménez-Periáñez, A., et al.
Publicado: (2013)

The efficacy of tumor debulking surgery is improved by adjuvant immunotherapy using imiquimod and anti-CD40
por: Khong, Andrea, et al.
Publicado: (2014)

Hsp70 enhances presentation of FMDV antigen to bovine CD4(+) T cells in vitro
por: McLaughlin, Kerry, et al.
Publicado: (2010)

Antigen Processing and Remodeling of the Endosomal Pathway: Requirements for Antigen Cross-Presentation
por: Compeer, Ewoud Bernardus, et al.
Publicado: (2012)

Cuprizone feed formulation influences the extent of demyelinating disease pathology
por: Toomey, Lillian M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qlk2bjib2eo2u4cnkjk9jfcma6