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Leukemic Stem Cell Frequency: A Strong Biomarker for Clinical Outcome in Acute Myeloid Leukemia
INTRODUCTION: Treatment failure in acute myeloid leukemia is probably caused by the presence of leukemia initiating cells, also referred to as leukemic stem cells, at diagnosis and their persistence after therapy. Specific identification of leukemia stem cells and their discrimination from normal he...
Autores principales: | Terwijn, Monique, Zeijlemaker, Wendelien, Kelder, Angèle, Rutten, Arjo P., Snel, Alexander N., Scholten, Willemijn J., Pabst, Thomas, Verhoef, Gregor, Löwenberg, Bob, Zweegman, Sonja, Ossenkoppele, Gert J., Schuurhuis, Gerrit J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171508/ https://www.ncbi.nlm.nih.gov/pubmed/25244440 http://dx.doi.org/10.1371/journal.pone.0107587 |
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