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Prognostic Value of Polycomb Proteins EZH2, BMI1 and SUZ12 and Histone Modification H3K27me3 in Colorectal Cancer

Numerous changes in epigenetic mechanisms have been described in various types of tumors. In search for new biomarkers, we investigated the expression of Polycomb-group (PcG) proteins EZH2, BMI1 and SUZ12 and associated histone modification H3K27me3 in colorectal cancer. Nuclear expression of PcG pr...

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Detalles Bibliográficos
Autores principales: Benard, Anne, Goossens-Beumer, Inès J., van Hoesel, Anneke Q., Horati, Hamed, Putter, Hein, Zeestraten, Eliane C. M., van de Velde, Cornelis J. H., Kuppen, Peter J. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171510/
https://www.ncbi.nlm.nih.gov/pubmed/25243792
http://dx.doi.org/10.1371/journal.pone.0108265