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Novel Camelid Antibody Fragments Targeting Recombinant Nucleoprotein of Araucaria hantavirus: A Prototype for an Early Diagnosis of Hantavirus Pulmonary Syndrome
In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH. Their particular characteristics make VHHs interesting tools for drug-delivery, passive immunotherapy and hig...
Autores principales: | Pereira, Soraya S., Moreira-Dill, Leandro S., Morais, Michelle S. S., Prado, Nidiane D. R., Barros, Marcos L., Koishi, Andrea C., Mazarrotto, Giovanny A. C. A., Gonçalves, Giselle M., Zuliani, Juliana P., Calderon, Leonardo A., Soares, Andreimar M., Pereira da Silva, Luiz H., Duarte dos Santos, Claudia N., Fernandes, Carla F. C., Stabeli, Rodrigo G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171512/ https://www.ncbi.nlm.nih.gov/pubmed/25243411 http://dx.doi.org/10.1371/journal.pone.0108067 |
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