Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway

BACKGROUND: Prostate cancer (PCa) is the second leading cause of cancer mortality of men in Western countries. The androgen receptor (AR) and AR-agonists (androgens) are required for the development and progression of the normal prostate as well as PCa. However, it is discussed that in addition to t...

Descripción completa

Detalles Bibliográficos
Autores principales: Roediger, Julia, Hessenkemper, Wiebke, Bartsch, Sophie, Manvelyan, Marina, Huettner, Soeren S, Liehr, Thomas, Esmaeili, Mohsen, Foller, Susan, Petersen, Iver, Grimm, Marc-Oliver, Baniahmad, Aria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171558/
https://www.ncbi.nlm.nih.gov/pubmed/25216853
http://dx.doi.org/10.1186/1476-4598-13-214

Ejemplares similares

Ejemplares similares