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Induction of integrin α(2) in a highly bone metastatic human prostate cancer cell line: roles of RANKL and AR under three-dimensional suspension culture
BACKGROUND: Prostate cancer (PCa) bone metastasis can be markedly enhanced by increased receptor activator of NF kappa-B ligand (RANKL) expression in PCa cells. Molecular mechanisms that account for the increased predilection of PCa for bone include increased bone turnover, promotion of PCa cell gro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171564/ https://www.ncbi.nlm.nih.gov/pubmed/25200184 http://dx.doi.org/10.1186/1476-4598-13-208 |