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Brachyury cooperates with Wnt/β-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells
BACKGROUND: The formation of the primitive streak is the first visible sign of gastrulation, the process by which the three germ layers are formed from a single epithelium during early development. Embryonic stem cells (ESCs) provide a good system for understanding the molecular and cellular events...
Autores principales: | Turner, David A, Rué, Pau, Mackenzie, Jonathan P, Davies, Eleanor, Martinez Arias, Alfonso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171571/ https://www.ncbi.nlm.nih.gov/pubmed/25115237 http://dx.doi.org/10.1186/s12915-014-0063-7 |
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