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Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers

BACKGROUND: Ribonucleotide reductase (RR) is an essential enzyme involved in DNA synthesis. We hypothesized that RR subunit M2 (RRM2) might be a novel prognostic and predictive biomarker for estrogen receptor (ER)-negative breast cancers. METHODS: Individual and pooled survival analyses were conduct...

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Detalles Bibliográficos
Autores principales:	Zhang, Hang, Liu, Xiyong, Warden, Charles D, Huang, Yasheng, Loera, Sofia, Xue, Lijun, Zhang, Suzhan, Chu, Peiguo, Zheng, Shu, Yen, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171582/ https://www.ncbi.nlm.nih.gov/pubmed/25213022 http://dx.doi.org/10.1186/1471-2407-14-664

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