The NF1 gene revisited – from bench to bedside

Neurofibromatosis type 1 (NF1) is a relatively common tumour predisposition syndrome related to germline aberrations of NF1, a tumour suppressor gene. The gene product neurofibromin is a negative regulator of the Ras cellular proliferation pathway, and also exerts tumour suppression via other mechan...

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Detalles Bibliográficos
Autores principales: Yap, Yoon-Sim, McPherson, John R, Ong, Choon-Kiat, Rozen, Steven G, Teh, Bin-Tean, Lee, Ann SG, Callen, David F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171599/
https://www.ncbi.nlm.nih.gov/pubmed/25026295

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