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Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition (EMT) in zebrafish
Aberration in DNA replication is a major cause to genome instability that is a hallmark of cancer cells. Cell division cycle 6 (Cdc6) and c-Myc have a critical role in the initiation of DNA replication. However, whether their interaction induces epithelial-mesenchymal transition (EMT) and promotes t...
Autores principales: | Chen, Ching-Hung, Lin, Dar-Shong, Cheng, Chieh-Wen, Lin, Chun-Ju, Lo, Yu-Kang, Yen, Chueh-Chuan, Lee, Alan Yueh-Luen, Hsiao, Chung-Der |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171631/ https://www.ncbi.nlm.nih.gov/pubmed/25051368 |
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