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Synthesis of Pyrimidine Incorporated Piperazine Derivatives and their Antimicrobial Activity

Thiophene substituted chalcones (1a-e) were cyclised with thiourea in presence of potassium hydroxide to get 4-substituted-6-(thiophen-2-yl)pyrimidine-2-thiols (2a-e) which were then stirred with methyl iodide to obtain 4-substituted-2-(methylsulfanyl)-6-(thiophen-2-yl)pyrimidines (3a-e). Compounds...

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Detalles Bibliográficos
Autores principales: Thriveni, K. S., Padmashali, B., Siddesh, M. B., Sandeep, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171870/
https://www.ncbi.nlm.nih.gov/pubmed/25284931