Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A(2), cyclooxygenases, lipoxygenase and pro-inflammatory cytokines

Arachidonic acid metabolism leads to the generation of key lipid mediators which play a fundamental role during inflammation. The inhibition of enzymes involved in arachidonic acid metabolism has been considered as a synergistic anti-inflammatory effect with enhanced spectrum of activity. A series o...

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Detalles Bibliográficos
Autores principales: Jantan, Ibrahim, Bukhari, Syed Nasir Abbas, Adekoya, Olayiwola A, Sylte, Ingebrigt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172049/
https://www.ncbi.nlm.nih.gov/pubmed/25258510
http://dx.doi.org/10.2147/DDDT.S67370

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