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Inhibition of urokinase plasminogen activator “uPA” activity alters ethanol consumption and conditioned place preference in mice

Urokinase plasminogen activator, uPA, is a serine protease implicated in addiction to drugs of abuse. Using its specific inhibitor, B428, we and others have characterized the role of uPA in the rewarding properties of psychostimulants, including cocaine and amphetamine, but none have examined the ro...

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Detalles Bibliográficos
Autores principales: Al Maamari, Elyazia, Al Ameri, Mouza, Al Mansouri, Shamma, Bahi, Amine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172050/
https://www.ncbi.nlm.nih.gov/pubmed/25258509
http://dx.doi.org/10.2147/DDDT.S68636