The current research status of normal tension glaucoma

Normal tension glaucoma (NTG) is a progressive optic neuropathy that mimics primary open-angle glaucoma, but lacks the findings of elevated intraocular pressure or other mitigating factors that can lead to optic neuropathy. The present review summarized the causes, genetics, and mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: Mi, Xue-Song, Yuan, Ti-Fei, So, Kwok-Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172068/
https://www.ncbi.nlm.nih.gov/pubmed/25258525
http://dx.doi.org/10.2147/CIA.S67263
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author Mi, Xue-Song
Yuan, Ti-Fei
So, Kwok-Fai
author_facet Mi, Xue-Song
Yuan, Ti-Fei
So, Kwok-Fai
author_sort Mi, Xue-Song
collection PubMed
description Normal tension glaucoma (NTG) is a progressive optic neuropathy that mimics primary open-angle glaucoma, but lacks the findings of elevated intraocular pressure or other mitigating factors that can lead to optic neuropathy. The present review summarized the causes, genetics, and mechanisms underlying NTG in both animal models and human patients. We also proposed that the neurovascular unit is a therapeutic target for NTG management.
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spelling pubmed-41720682014-09-25 The current research status of normal tension glaucoma Mi, Xue-Song Yuan, Ti-Fei So, Kwok-Fai Clin Interv Aging Review Normal tension glaucoma (NTG) is a progressive optic neuropathy that mimics primary open-angle glaucoma, but lacks the findings of elevated intraocular pressure or other mitigating factors that can lead to optic neuropathy. The present review summarized the causes, genetics, and mechanisms underlying NTG in both animal models and human patients. We also proposed that the neurovascular unit is a therapeutic target for NTG management. Dove Medical Press 2014-09-16 /pmc/articles/PMC4172068/ /pubmed/25258525 http://dx.doi.org/10.2147/CIA.S67263 Text en © 2014 Mi et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Mi, Xue-Song
Yuan, Ti-Fei
So, Kwok-Fai
The current research status of normal tension glaucoma
title The current research status of normal tension glaucoma
title_full The current research status of normal tension glaucoma
title_fullStr The current research status of normal tension glaucoma
title_full_unstemmed The current research status of normal tension glaucoma
title_short The current research status of normal tension glaucoma
title_sort current research status of normal tension glaucoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172068/
https://www.ncbi.nlm.nih.gov/pubmed/25258525
http://dx.doi.org/10.2147/CIA.S67263
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