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Nanotetrac targets integrin αvβ3 on tumor cells to disorder cell defense pathways and block angiogenesis

The extracellular domain of integrin αvβ3 contains a receptor for thyroid hormone and hormone analogs. The integrin is amply expressed by tumor cells and dividing blood vessel cells. The proangiogenic properties of thyroid hormone and the capacity of the hormone to promote cancer cell proliferation...

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Detalles Bibliográficos
Autores principales:	Davis, Paul J, Lin, Hung-Yun, Sudha, Thangirala, Yalcin, Murat, Tang, Heng-Yuan, Hercbergs, Aleck, Leith, John T, Luidens, Mary K, Ashur-Fabian, Osnat, Incerpi, Sandra, Mousa, Shaker A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172128/ https://www.ncbi.nlm.nih.gov/pubmed/25258542 http://dx.doi.org/10.2147/OTT.S67393

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