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Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X

The T cell hyperproliferation and autoimmune phenotypes that manifest in mice lacking E3 ubiquitin ligases such as Cbl, ITCH, or GRAIL highlight the importance of ubiquitination for the maintenance of peripheral T cell tolerance. Less is known, however, about the deubiquitinating enzymes that regula...

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Detalles Bibliográficos
Autores principales:	Naik, Edwina, Webster, Joshua D., DeVoss, Jason, Liu, Jinfeng, Suriben, Rowena, Dixit, Vishva M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172213/ https://www.ncbi.nlm.nih.gov/pubmed/25200027 http://dx.doi.org/10.1084/jem.20140860

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