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WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc–dependent manner

Hematopoiesis is fully dependent on hematopoietic stem cells (HSCs) that possess the capacity to self-renew and differentiate into all blood cell lineages. WASH, Wiskott–Aldrich syndrome protein (WASP) and SCAR homologue (WASH) is involved in endosomal sorting as an actin-nucleating protein. Here, w...

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Detalles Bibliográficos
Autores principales:	Xia, Pengyan, Wang, Shuo, Huang, Guanling, Zhu, Pingping, Li, Man, Ye, Buqing, Du, Ying, Fan, Zusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172220/ https://www.ncbi.nlm.nih.gov/pubmed/25225459 http://dx.doi.org/10.1084/jem.20140169

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