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Transforming Growth Factor β and Insulin Signal Changes in Stromal Fibroblasts of Individual Keratoconus Patients

Keratoconus (KC) is a complex thinning disease of the cornea that often requires transplantation. The underlying pathogenic molecular changes in this disease are poorly understood. Earlier studies reported oxidative stress, metabolic dysfunctions and accelerated death of stromal keratocytes in kerat...

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Detalles Bibliográficos
Autores principales: Foster, James, Wu, Wai-Hong, Scott, Sherri-Gae, Bassi, Mehak, Mohan, Divya, Daoud, Yassine, Stark, Walter J., Jun, Albert S., Chakravarti, Shukti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172437/
https://www.ncbi.nlm.nih.gov/pubmed/25247416
http://dx.doi.org/10.1371/journal.pone.0106556

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