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Transforming Growth Factor β and Insulin Signal Changes in Stromal Fibroblasts of Individual Keratoconus Patients
Keratoconus (KC) is a complex thinning disease of the cornea that often requires transplantation. The underlying pathogenic molecular changes in this disease are poorly understood. Earlier studies reported oxidative stress, metabolic dysfunctions and accelerated death of stromal keratocytes in kerat...
Autores principales: | Foster, James, Wu, Wai-Hong, Scott, Sherri-Gae, Bassi, Mehak, Mohan, Divya, Daoud, Yassine, Stark, Walter J., Jun, Albert S., Chakravarti, Shukti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172437/ https://www.ncbi.nlm.nih.gov/pubmed/25247416 http://dx.doi.org/10.1371/journal.pone.0106556 |
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