Role of Ser102 and Ser104 as Regulators of cGMP Hydrolysis by PDE5A

BACKGROUND: Phosphodiesterases (PDEs) cleave phosphodiester bonds in cyclic nucleotides and play diverse roles in cell biology. PDE5A is a cytoplasmic phosphodiesterase which specifically degrades cyclic guanosine monophosphate (cGMP), a cell signaling molecule that plays important roles in neuronal...

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Detalles Bibliográficos
Autores principales: Carøe Nordgaard, Julie, Kruse, Lars Schack, Gammeltoft, Steen, Kruuse, Christina Rostrup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172485/
https://www.ncbi.nlm.nih.gov/pubmed/25247292
http://dx.doi.org/10.1371/journal.pone.0107627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172485/
https://www.ncbi.nlm.nih.gov/pubmed/25247292
http://dx.doi.org/10.1371/journal.pone.0107627

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