Deleted in Breast Cancer 1 regulates cellular senescence during obesity

Chronic obesity leads to inflammation, tissue dysfunction, and cellular senescence. It was proposed that cellular senescence during obesity and aging drives inflammation and dysfunction. Consistent with this, clearance of senescent cells increases healthspan in progeroid mice. Here, we show that the...

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Detalles Bibliográficos
Autores principales: Escande, Carlos, Nin, Veronica, Pirtskhalava, Tamar, Chini, Claudia C, Thereza Barbosa, Maria, Mathison, Angela, Urrutia, Raul, Tchkonia, Tamar, Kirkland, James L, Chini, Eduardo N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Short Takes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172532/
https://www.ncbi.nlm.nih.gov/pubmed/24992635
http://dx.doi.org/10.1111/acel.12235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172532/
https://www.ncbi.nlm.nih.gov/pubmed/24992635
http://dx.doi.org/10.1111/acel.12235

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