Cargando…
Conceptualizing Cancer Drugs as Classifiers
Cancer and healthy cells have distinct distributions of molecular properties and thus respond differently to drugs. Cancer drugs ideally kill cancer cells while limiting harm to healthy cells. However, the inherent variance among cells in both cancer and healthy cell populations increases the diffic...
Autores principales: | Lawlor, Patrick Nathan, Kalisky, Tomer, Rosner, Robert, Rosner, Marsha Rich, Kording, Konrad Paul |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172566/ https://www.ncbi.nlm.nih.gov/pubmed/25248130 http://dx.doi.org/10.1371/journal.pone.0106444 |
Ejemplares similares
-
Harnessing RKIP to Combat Heart Disease and Cancer
por: Lorenz, Kristina, et al.
Publicado: (2022) -
MAP kinase meets mitosis: A role for Raf Kinase Inhibitory Protein in spindle checkpoint regulation
por: Rosner, Marsha Rich
Publicado: (2007) -
Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer
por: Frank, Steven A., et al.
Publicado: (2012) -
RKIP Suppresses Breast Cancer Metastasis to the Bone by Regulating Stroma-Associated Genes
por: Bevilacqua, Elena, et al.
Publicado: (2012) -
Targeting Raf Kinase Inhibitory Protein Regulation and Function
por: Yesilkanal, Ali Ekrem, et al.
Publicado: (2018)