Myeloid Derived Suppressor Cells Are Present at High Frequency in Neonates and Suppress In Vitro T Cell Responses

Over 4 million infants die each year from infections, many of which are vaccine-preventable. Young infants respond relatively poorly to many infections and vaccines, but the basis of reduced immunity in infants is ill defined. We sought to investigate whether myeloid-derived suppressor cells (MDSC)...

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Detalles Bibliográficos
Autores principales: Gervassi, Ana, Lejarcegui, Nicholas, Dross, Sandra, Jacobson, Amanda, Itaya, Grace, Kidzeru, Elvis, Gantt, Soren, Jaspan, Heather, Horton, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172591/
https://www.ncbi.nlm.nih.gov/pubmed/25248150
http://dx.doi.org/10.1371/journal.pone.0107816

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