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The Chromatin Remodeling Factor CHD5 Is a Transcriptional Repressor of WEE1

Loss of the chromatin remodeling ATPase CHD5 has been linked to the progression of neuroblastoma tumors, yet the underlying mechanisms behind the tumor suppressor role of CHD5 are unknown. In this study, we purified the human CHD5 complex and found that CHD5 is a component of the full NuRD transcrip...

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Detalles Bibliográficos
Autores principales:	Quan, Jinhua, Adelmant, Guillaume, Marto, Jarrod A., Look, A. Thomas, Yusufzai, Timur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172601/ https://www.ncbi.nlm.nih.gov/pubmed/25247294 http://dx.doi.org/10.1371/journal.pone.0108066

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