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A Full-Length Plasmodium falciparum Recombinant Circumsporozoite Protein Expressed by Pseudomonas fluorescens Platform as a Malaria Vaccine Candidate
The circumsporozoite protein (CSP) of Plasmodium falciparum is a major surface protein, which forms a dense coat on the sporozoite's surface. Preclinical research on CSP and clinical evaluation of a CSP fragment-based RTS, S/AS01 vaccine have demonstrated a modest degree of protection against P...
Autores principales: | Noe, Amy R., Espinosa, Diego, Li, Xiangming, Coelho-dos-Reis, Jordana G. A., Funakoshi, Ryota, Giardina, Steve, Jin, Hongfan, Retallack, Diane M., Haverstock, Ryan, Allen, Jeffrey R., Vedvick, Thomas S., Fox, Christopher B., Reed, Steven G., Ayala, Ramses, Roberts, Brian, Winram, Scott B., Sacci, John, Tsuji, Moriya, Zavala, Fidel, Gutierrez, Gabriel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172688/ https://www.ncbi.nlm.nih.gov/pubmed/25247295 http://dx.doi.org/10.1371/journal.pone.0107764 |
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