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p53 Down Regulates PDGF-Induced Formation of Circular Dorsal Ruffles in Rat Aortic Smooth Muscle Cells

The tumor suppressor, p53, negatively regulates cell migration and invasion in addition to its role in apoptosis, cell cycle regulation and senescence. Here, we study the roles of p53 in PDGF-induced circular dorsal ruffle (CDR) formation in rat aortic smooth muscle (RASM) cells. In primary and immo...

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Detalles Bibliográficos
Autores principales: Payne, Laura J., Eves, Robert L., Jia, Lilly, Mak, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172730/
https://www.ncbi.nlm.nih.gov/pubmed/25247424
http://dx.doi.org/10.1371/journal.pone.0108257