Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics

BACKGROUND: Autophagy is a vesicle-mediated pathway for lysosomal degradation, essential under basal and stressed conditions. Various cellular components, including specific proteins, protein aggregates, organelles and intracellular pathogens, are targets for autophagic degradation. Thereby, autopha...

Descripción completa

Detalles Bibliográficos
Autores principales: Börlin, Christoph S, Lang, Verena, Hamacher-Brady, Anne, Brady, Nathan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172826/
https://www.ncbi.nlm.nih.gov/pubmed/25214434
http://dx.doi.org/10.1186/s12964-014-0056-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172826/
https://www.ncbi.nlm.nih.gov/pubmed/25214434
http://dx.doi.org/10.1186/s12964-014-0056-8

Ejemplares similares