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Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics

BACKGROUND: Autophagy is a vesicle-mediated pathway for lysosomal degradation, essential under basal and stressed conditions. Various cellular components, including specific proteins, protein aggregates, organelles and intracellular pathogens, are targets for autophagic degradation. Thereby, autopha...

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Detalles Bibliográficos
Autores principales:	Börlin, Christoph S, Lang, Verena, Hamacher-Brady, Anne, Brady, Nathan R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172826/ https://www.ncbi.nlm.nih.gov/pubmed/25214434 http://dx.doi.org/10.1186/s12964-014-0056-8

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