Transient TNF regulates the self-renewing capacity of stem-like label-retaining cells in sphere and skin equivalent models of melanoma

BACKGROUND: It is well established that inflammation promotes cancer, including melanoma, although the exact mechanisms involved are less known. In this study, we tested the hypothesis that inflammatory factors affect the cancer stem cell (CSC) compartment responsible for tumor development and relap...

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Detalles Bibliográficos
Autores principales: Ostyn, Pauline, El Machhour, Raja, Begard, Severine, Kotecki, Nuria, Vandomme, Jerome, Flamenco, Pilar, Segard, Pascaline, Masselot, Bernadette, Formstecher, Pierre, Touil, Yasmine, Polakowska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172864/
https://www.ncbi.nlm.nih.gov/pubmed/25223735
http://dx.doi.org/10.1186/s12964-014-0052-z

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