Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer’s disease mouse model

BACKGROUND: Profound synapse loss is one of the major pathological hallmarks associated with Alzheimer’s disease, which might underlie memory impairment. Our previous work demonstrates that magnesium ion is a critical factor in controlling synapse density/plasticity. Here, we tested whether elevatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wei, Yu, Jia, Liu, Yong, Huang, Xiaojie, Abumaria, Nashat, Zhu, Ying, Huang, Xian, Xiong, Wenxiang, Ren, Chi, Liu, Xian-Guo, Chui, Dehua, Liu, Guosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172865/
https://www.ncbi.nlm.nih.gov/pubmed/25213836
http://dx.doi.org/10.1186/s13041-014-0065-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172865/
https://www.ncbi.nlm.nih.gov/pubmed/25213836
http://dx.doi.org/10.1186/s13041-014-0065-y

Ejemplares similares