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Tumor suppressor miR-1 restrains epithelial-mesenchymal transition and metastasis of colorectal carcinoma via the MAPK and PI3K/AKT pathway
Aberrant expression of miR-1 has been implicated in various cancers. However, the mechanisms underlying the role of miR-1 in CRC progression still have not been clarified clearly. Here, we showed the decreased expression of miR-1 in colorectal carcinoma (CRC) tissues and cell lines. Ectopic introduc...
Autores principales: | Xu, Lijun, Zhang, Yue, Wang, Hui, Zhang, Guanhua, Ding, Yanqing, Zhao, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172896/ https://www.ncbi.nlm.nih.gov/pubmed/25196260 http://dx.doi.org/10.1186/s12967-014-0244-8 |
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