Suitable extracellular oxidoreduction potential inhibit rex regulation and effect central carbon and energy metabolism in Saccharopolyspora spinosa

BACKGROUND: Polyketides, such as spinosad, are mainly synthesized in the stationary phase of the fermentation. The synthesis of these compounds requires many primary metabolites, such as acetyl-CoA, propinyl-CoA, NADPH, and succinyl-CoA. Their synthesis is also significantly influenced by NADH/NAD(+...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangmei, Xue, Chaoyou, Zhao, Fanglong, Li, Dashuai, Yin, Jing, Zhang, Chuanbo, Caiyin, Qinggele, Lu, Wenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172946/
https://www.ncbi.nlm.nih.gov/pubmed/25158803
http://dx.doi.org/10.1186/s12934-014-0098-z

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