Cargando…
The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription
The SAGA (Spt–Ada–Gcn5 acetyltransferase) coactivator complex contains distinct chromatin-modifying activities and is recruited by DNA-bound activators to regulate the expression of a subset of genes. Surprisingly, recent studies revealed little overlap between genome-wide SAGA-binding profiles and...
Autores principales: | Bonnet, Jacques, Wang, Chen-Yi, Baptista, Tiago, Vincent, Stéphane D., Hsiao, Wei-Chun, Stierle, Matthieu, Kao, Cheng-Fu, Tora, László, Devys, Didier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173158/ https://www.ncbi.nlm.nih.gov/pubmed/25228644 http://dx.doi.org/10.1101/gad.250225.114 |
Ejemplares similares
-
The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms
por: Fischer, Veronique, et al.
Publicado: (2021) -
SAGA is a general cofactor for RNA polymerase II transcription
por: Baptista, Tiago, et al.
Publicado: (2017) -
SUPT3H-less SAGA coactivator can assemble and function without significantly perturbing RNA polymerase II transcription in mammalian cells
por: Fischer, Veronique, et al.
Publicado: (2022) -
Global role for coactivator complexes in RNA polymerase II transcription
por: Fischer, Veronique, et al.
Publicado: (2018) -
SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development
por: El-Saafin, Farrah, et al.
Publicado: (2022)