Holmes tremor in a patient with progressive multifocal leukoencephalopathy

BACKGROUND: Progressive multifocal leukencephalopathy (PML) is a rare, sometimes fatal viral disease in patients with primary or secondary immunosuppression. CASE DESCRIPTION: A 57-year-old immunocompetent female with intractable Holmes tremor and elongated unique brainstem lesion reported to our ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Gunness, Vimal Raj Nitish, Dooms, Georges, Wauschkuhn, Bernd, Feiden, Wolfgang, Hertel, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Surgical Neurology International: Stereotactic
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173311/
https://www.ncbi.nlm.nih.gov/pubmed/25289172
http://dx.doi.org/10.4103/2152-7806.140205
Descripción
Sumario:BACKGROUND: Progressive multifocal leukencephalopathy (PML) is a rare, sometimes fatal viral disease in patients with primary or secondary immunosuppression. CASE DESCRIPTION: A 57-year-old immunocompetent female with intractable Holmes tremor and elongated unique brainstem lesion reported to our hospital. The cerebrospinal fluid (CSF) screening for John Cunningham virus was negative and the diagnosis was established by brain biopsy. The course was rapidly fatal. CONCLUSION: This atypical presentation of PML in an immunocompetent patient illustrates that diagnosis can be missed without brain biopsy.

Ejemplares similares