Cargando…
Comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery
CONTEXT: Ropivacaine, s-enantiomer of amide local anaesthetic produces differential neural blockade with less motor blockade, cardiovascular and neurological toxicity makes it suitable for day case surgery in children. AIMS: To compare the effectiveness of Inj. Ropivacaine (0.2 or 0.25%) or Inj. Bup...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173527/ https://www.ncbi.nlm.nih.gov/pubmed/25885835 http://dx.doi.org/10.4103/0259-1162.118965 |
_version_ | 1782336214226960384 |
---|---|
author | Doctor, Tarlika P. Dalwadi, Divyang B. Abraham, Lissa Shah, Namrata Chadha, Indu A. Shah, Bharat J. |
author_facet | Doctor, Tarlika P. Dalwadi, Divyang B. Abraham, Lissa Shah, Namrata Chadha, Indu A. Shah, Bharat J. |
author_sort | Doctor, Tarlika P. |
collection | PubMed |
description | CONTEXT: Ropivacaine, s-enantiomer of amide local anaesthetic produces differential neural blockade with less motor blockade, cardiovascular and neurological toxicity makes it suitable for day case surgery in children. AIMS: To compare the effectiveness of Inj. Ropivacaine (0.2 or 0.25%) or Inj. Bupivacaine (0.25%) with fentanyl in caudal block for intra and postoperative analgesia. SETTINGS AND DESIGN: Double blind retrospective randomized study. MATERIALS AND METHODS: All the patients (n=112) varying from age group 3.02 ± 3.29 years belonging to ASA I-IV were randomly allocated to receive caudal analgesia Group BF inj. Bupivacaine (0.25%, 2 mg/kg) + Inj. Fentany1 μg/kg (n=70) and group RF: Inj. Ropivacaine (0.25% or 0.2%, 2 mg/kg) + inj. Fentanyl 1 μg/kg (n=42). We monitored vitals and requirement of inhalational gases inraoperatively and also observed pain by pain score (Visual Analogue Score in verbal group and Objective Pain Scale in nonverbal group) and vitals postoperatively. We used rescue analgesics (inj. Paracetamol 5 mg/kg iv) when VAS score ≥4. STATISTICAL ANALYSIS: Student's t-test. RESULTS: Duration of analgesia was prolonged in both group RF and BF. Time for first rescue analgesic for group RF (6.1 ± 1.1 hr) compared to group BF (5.6 ± 0.9 hr). Haemodynamic stability and less requirement of inhalation agent intraoperatively with group RF than others. CONCLUSIONS: Ropivacaine with Fentanyl found to be better combination for pediatric surgeries for below umbilical surgeries as an adjuvant to general anaesthesia or sole technique with chances of less complication with high success rate. |
format | Online Article Text |
id | pubmed-4173527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41735272014-10-22 Comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery Doctor, Tarlika P. Dalwadi, Divyang B. Abraham, Lissa Shah, Namrata Chadha, Indu A. Shah, Bharat J. Anesth Essays Res Original Article CONTEXT: Ropivacaine, s-enantiomer of amide local anaesthetic produces differential neural blockade with less motor blockade, cardiovascular and neurological toxicity makes it suitable for day case surgery in children. AIMS: To compare the effectiveness of Inj. Ropivacaine (0.2 or 0.25%) or Inj. Bupivacaine (0.25%) with fentanyl in caudal block for intra and postoperative analgesia. SETTINGS AND DESIGN: Double blind retrospective randomized study. MATERIALS AND METHODS: All the patients (n=112) varying from age group 3.02 ± 3.29 years belonging to ASA I-IV were randomly allocated to receive caudal analgesia Group BF inj. Bupivacaine (0.25%, 2 mg/kg) + Inj. Fentany1 μg/kg (n=70) and group RF: Inj. Ropivacaine (0.25% or 0.2%, 2 mg/kg) + inj. Fentanyl 1 μg/kg (n=42). We monitored vitals and requirement of inhalational gases inraoperatively and also observed pain by pain score (Visual Analogue Score in verbal group and Objective Pain Scale in nonverbal group) and vitals postoperatively. We used rescue analgesics (inj. Paracetamol 5 mg/kg iv) when VAS score ≥4. STATISTICAL ANALYSIS: Student's t-test. RESULTS: Duration of analgesia was prolonged in both group RF and BF. Time for first rescue analgesic for group RF (6.1 ± 1.1 hr) compared to group BF (5.6 ± 0.9 hr). Haemodynamic stability and less requirement of inhalation agent intraoperatively with group RF than others. CONCLUSIONS: Ropivacaine with Fentanyl found to be better combination for pediatric surgeries for below umbilical surgeries as an adjuvant to general anaesthesia or sole technique with chances of less complication with high success rate. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC4173527/ /pubmed/25885835 http://dx.doi.org/10.4103/0259-1162.118965 Text en Copyright: © Anesthesia: Essays and Researches http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Doctor, Tarlika P. Dalwadi, Divyang B. Abraham, Lissa Shah, Namrata Chadha, Indu A. Shah, Bharat J. Comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery |
title | Comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery |
title_full | Comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery |
title_fullStr | Comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery |
title_full_unstemmed | Comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery |
title_short | Comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery |
title_sort | comparison of ropivacaine and bupivacaine with fentanyl for caudal epidural in pediatric surgery |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173527/ https://www.ncbi.nlm.nih.gov/pubmed/25885835 http://dx.doi.org/10.4103/0259-1162.118965 |
work_keys_str_mv | AT doctortarlikap comparisonofropivacaineandbupivacainewithfentanylforcaudalepiduralinpediatricsurgery AT dalwadidivyangb comparisonofropivacaineandbupivacainewithfentanylforcaudalepiduralinpediatricsurgery AT abrahamlissa comparisonofropivacaineandbupivacainewithfentanylforcaudalepiduralinpediatricsurgery AT shahnamrata comparisonofropivacaineandbupivacainewithfentanylforcaudalepiduralinpediatricsurgery AT chadhaindua comparisonofropivacaineandbupivacainewithfentanylforcaudalepiduralinpediatricsurgery AT shahbharatj comparisonofropivacaineandbupivacainewithfentanylforcaudalepiduralinpediatricsurgery |