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Opioid-induced respiratory depression: reversal by non-opioid drugs

The human body is critically dependent on the ventilatory control system for adequate uptake of oxygen and removal of carbon dioxide (CO(2)). Potent opioid analgesics, through their actions on μ-opioid receptor (MOR) expressed on respiratory neurons in the brainstem, depress ventilation. Opioid-indu...

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Detalles Bibliográficos
Autores principales: van der Schier, Rutger, Roozekrans, Margot, van Velzen, Monique, Dahan, Albert, Niesters, Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173639/
https://www.ncbi.nlm.nih.gov/pubmed/25343036
http://dx.doi.org/10.12703/P6-79