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Opioid-induced respiratory depression: reversal by non-opioid drugs
The human body is critically dependent on the ventilatory control system for adequate uptake of oxygen and removal of carbon dioxide (CO(2)). Potent opioid analgesics, through their actions on μ-opioid receptor (MOR) expressed on respiratory neurons in the brainstem, depress ventilation. Opioid-indu...
Autores principales: | van der Schier, Rutger, Roozekrans, Margot, van Velzen, Monique, Dahan, Albert, Niesters, Marieke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty of 1000 Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173639/ https://www.ncbi.nlm.nih.gov/pubmed/25343036 http://dx.doi.org/10.12703/P6-79 |
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