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A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea

BACKGROUND: Irritable bowel syndrome with diarrhoea (IBS-D) is particularly debilitating due to urgency and episodic incontinence. Some 5-hydroxytryptamine 3 (5-HT3) receptor antagonists (5-HT3RAs) have proven effective but have serious side effects. Ondansetron, also a 5-HT3RA, has been widely used...

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Detalles Bibliográficos
Autores principales: Garsed, Klara, Chernova, Julia, Hastings, Margaret, Lam, Ching, Marciani, Luca, Singh, Gulzar, Henry, Amanda, Hall, Ian, Whorwell, Peter, Spiller, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173656/
https://www.ncbi.nlm.nih.gov/pubmed/24334242
http://dx.doi.org/10.1136/gutjnl-2013-305989