Systemic administration of 6-OHDA to rhesus monkeys upregulates HLA-DR expression in brain microvasculature

BACKGROUND: We recently developed a nonhuman primate model of cardiac dysautonomia by systemic dosing of the catecholaminergic neurotoxin 6-hydroxydopamine (6-OHDA). The aim of this study was to assess whether systemic 6-OHDA affects the central nervous system of nonhuman primates, in particular the...

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Detalles Bibliográficos
Autores principales: Joers, Valerie, Vermilyea, Scott, Dilley, Kristine, Emborg, Marina E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173661/
https://www.ncbi.nlm.nih.gov/pubmed/25258551
http://dx.doi.org/10.2147/JIR.S67285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173661/
https://www.ncbi.nlm.nih.gov/pubmed/25258551
http://dx.doi.org/10.2147/JIR.S67285

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