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Systemic administration of 6-OHDA to rhesus monkeys upregulates HLA-DR expression in brain microvasculature
BACKGROUND: We recently developed a nonhuman primate model of cardiac dysautonomia by systemic dosing of the catecholaminergic neurotoxin 6-hydroxydopamine (6-OHDA). The aim of this study was to assess whether systemic 6-OHDA affects the central nervous system of nonhuman primates, in particular the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173661/ https://www.ncbi.nlm.nih.gov/pubmed/25258551 http://dx.doi.org/10.2147/JIR.S67285 |