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Engineering Persister-Specific Antibiotics with Synergistic Antimicrobial Functions
[Image: see text] Most antibiotics target growth processes and are ineffective against persister bacterial cells, which tolerate antibiotics due to their reduced metabolic activity. These persisters act as a genetic reservoir for resistant mutants and constitute a root cause of antibiotic resistance...
Autores principales: | Schmidt, Nathan W., Deshayes, Stephanie, Hawker, Sinead, Blacker, Alyssa, Kasko, Andrea M., Wong, Gerard C. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173747/ https://www.ncbi.nlm.nih.gov/pubmed/25130648 http://dx.doi.org/10.1021/nn502201a |
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