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Quantification of transient increase of the blood–brain barrier permeability to macromolecules by optimized focused ultrasound combined with microbubbles
Radioimmunotherapy using a radiolabeled monoclonal antibody that targets tumor cells has been shown to be efficient for the treatment of many malignant cancers, with reduced side effects. However, the blood–brain barrier (BBB) inhibits the transport of intravenous antibodies to tumors in the brain....
Autores principales: | Shi, Lingyan, Palacio-Mancheno, Paolo, Badami, Joseph, Shin, Da Wi, Zeng, Min, Cardoso, Luis, Tu, Raymond, Fu, Bingmei M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173757/ https://www.ncbi.nlm.nih.gov/pubmed/25258533 http://dx.doi.org/10.2147/IJN.S68882 |
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