Co-delivery of Doxorubicin and Bmi1 siRNA by Folate Receptor Targeted Liposomes Exhibits Enhanced Anti-Tumor Effects in vitro and in vivo

Bmi1 gene overexpression is found in various human tumors and has been shown as a potential target for gene treatment. However, siRNA-based treatments targeting Bmi1 gene have been restricted to limited delivery, low bioavailability and hence relatively reduced efficacy. To overcome these barriers,...

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Detalles Bibliográficos
Autores principales: Yang, Tan, Li, Bin, Qi, Shibo, Liu, Yong, Gai, Yongkang, Ye, Peng, Yang, Guang, Zhang, Wendian, Zhang, Peng, He, Xingxing, Li, Weijie, Zhang, Zhiping, Xiang, Guangya, Xu, Chuanrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173760/
https://www.ncbi.nlm.nih.gov/pubmed/25285163
http://dx.doi.org/10.7150/thno.9423

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