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A Case of Microstomia Subsequent to Toxic Epidermal Necrolysis Surgically Treated by Simple Technique

SUMMARY: Toxic epidermal necrolysis (TEN) is a rare but severe adverse dermatitis that is an autoimmune reaction to drugs such as nonsteroidal anti-inflammatory drugs. TEN most severely affects the mucous membranes including the mouth and could develop into microstomia; however, microstomia in relat...

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Detalles Bibliográficos
Autores principales: Mashiko, Takanobu, Minabe, Toshiharu, Oka, Aiko, Ohnishi, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173819/
https://www.ncbi.nlm.nih.gov/pubmed/25289215
http://dx.doi.org/10.1097/GOX.0b013e3182980067
Descripción
Sumario:SUMMARY: Toxic epidermal necrolysis (TEN) is a rare but severe adverse dermatitis that is an autoimmune reaction to drugs such as nonsteroidal anti-inflammatory drugs. TEN most severely affects the mucous membranes including the mouth and could develop into microstomia; however, microstomia in relation to TEN has rarely been reported in the literature. We describe an adult female patient who developed microstomia due to scar contracture of the bilateral oral commissures subsequent to TEN and was successfully treated by a simple surgical technique consisting solely of transverse incision of the commissure and longitudinal closure.