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Enhanced bioavailability and anthelmintic efficacy of mebendazole in redispersible microparticles with low-substituted hydroxypropylcellulose

BACKGROUND: Mebendazole (MBZ) is an extremely insoluble and therefore poorly absorbed drug and the variable clinical results may correlate with blood concentrations. The necessity of a prolonged high dose treatment of this drug increases the risk of adverse effects. METHODS: In the present study we...

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Detalles Bibliográficos
Autores principales:	de la Torre-Iglesias, Paloma Marina, García-Rodriguez, Juan José, Torrado, Guillermo, Torrado, Susana, Torrado-Santiago, Santiago, Bolás-Fernández, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174045/ https://www.ncbi.nlm.nih.gov/pubmed/25258515 http://dx.doi.org/10.2147/DDDT.S65561

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