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Systemic Nicardipine as an Adjunct to Combat Vasospasm after Prior Flap Failure

SUMMARY: Unrecognized or untreated vasospasm in microsurgery can lead to flap hypoperfusion and failure. Numerous strategies have been explored for their efficacy in potentiating vasodilation. We present a case of unrecognized vasospasm leading to flap failure followed by a second free flap reconstr...

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Autores principales: Michelotti, Brett F., Rajjoub, Samer, Johnson, T. Shane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174056/
https://www.ncbi.nlm.nih.gov/pubmed/25289249
http://dx.doi.org/10.1097/GOX.0b013e3182aa8747
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author Michelotti, Brett F.
Rajjoub, Samer
Johnson, T. Shane
author_facet Michelotti, Brett F.
Rajjoub, Samer
Johnson, T. Shane
author_sort Michelotti, Brett F.
collection PubMed
description SUMMARY: Unrecognized or untreated vasospasm in microsurgery can lead to flap hypoperfusion and failure. Numerous strategies have been explored for their efficacy in potentiating vasodilation. We present a case of unrecognized vasospasm leading to flap failure followed by a second free flap reconstruction in which severe vasospasm was treated with systemic nicardipine used as an adjunct to other more commonly employed antispasmodics. Although the literature investigating the use of systemic calcium channel blockade in microsurgery is limited, it should be considered an alternative when addressing arterial vasospasm.
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spelling pubmed-41740562014-10-06 Systemic Nicardipine as an Adjunct to Combat Vasospasm after Prior Flap Failure Michelotti, Brett F. Rajjoub, Samer Johnson, T. Shane Plast Reconstr Surg Glob Open Case Reports SUMMARY: Unrecognized or untreated vasospasm in microsurgery can lead to flap hypoperfusion and failure. Numerous strategies have been explored for their efficacy in potentiating vasodilation. We present a case of unrecognized vasospasm leading to flap failure followed by a second free flap reconstruction in which severe vasospasm was treated with systemic nicardipine used as an adjunct to other more commonly employed antispasmodics. Although the literature investigating the use of systemic calcium channel blockade in microsurgery is limited, it should be considered an alternative when addressing arterial vasospasm. Wolters Kluwer Health 2013-11-07 /pmc/articles/PMC4174056/ /pubmed/25289249 http://dx.doi.org/10.1097/GOX.0b013e3182aa8747 Text en Copyright © 2013 The Authors. Published by Lippincott Williams & Wilkins on behalf of The American Society of Plastic Surgeons. PRS Global Open is a publication of the American Society of Plastic Surgeons. http://creativecommons.org/licenses/by-nc-nd/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivitives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
spellingShingle Case Reports
Michelotti, Brett F.
Rajjoub, Samer
Johnson, T. Shane
Systemic Nicardipine as an Adjunct to Combat Vasospasm after Prior Flap Failure
title Systemic Nicardipine as an Adjunct to Combat Vasospasm after Prior Flap Failure
title_full Systemic Nicardipine as an Adjunct to Combat Vasospasm after Prior Flap Failure
title_fullStr Systemic Nicardipine as an Adjunct to Combat Vasospasm after Prior Flap Failure
title_full_unstemmed Systemic Nicardipine as an Adjunct to Combat Vasospasm after Prior Flap Failure
title_short Systemic Nicardipine as an Adjunct to Combat Vasospasm after Prior Flap Failure
title_sort systemic nicardipine as an adjunct to combat vasospasm after prior flap failure
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174056/
https://www.ncbi.nlm.nih.gov/pubmed/25289249
http://dx.doi.org/10.1097/GOX.0b013e3182aa8747
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