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Autologous Fat Grafting for Whole Breast Reconstruction
SUMMARY: This is the first reported case of a patient who had a single-stage large-volume breast reconstruction with autologous fat grafting, following rotation flap approach (RoFA) mastectomy. The purpose of this case study was to evaluate the viability of reconstruction of the breast by autologous...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174150/ https://www.ncbi.nlm.nih.gov/pubmed/25289318 http://dx.doi.org/10.1097/GOX.0000000000000075 |
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author | Howes, Benjamin H. L. Fosh, Beverley Watson, David I. Yip, Jia Miin Eaton, Michael Smallman, Andrea Dean, Nicola R. |
author_facet | Howes, Benjamin H. L. Fosh, Beverley Watson, David I. Yip, Jia Miin Eaton, Michael Smallman, Andrea Dean, Nicola R. |
author_sort | Howes, Benjamin H. L. |
collection | PubMed |
description | SUMMARY: This is the first reported case of a patient who had a single-stage large-volume breast reconstruction with autologous fat grafting, following rotation flap approach (RoFA) mastectomy. The purpose of this case study was to evaluate the viability of reconstruction of the breast by autologous fat grafting alone, in the context of RoFA mastectomy. The hypothesis was that there would be minimal interval loss of autologous fat on the whole breast reconstruction side. Right RoFA mastectomy was used for resection of an invasive primary breast cancer and resulted in the right breast skin envelope. Eleven months later, the patient underwent grafting of 400 ml of autologous fat into the skin envelope and underlying pectoralis major muscle. Outcome was assessed by using a validated 3D laser scan technique for quantitative breast volume measurement. Other outcome measures included the BREAST-Q questionnaire and 2D clinical photography. At 12-month follow-up, the patient was observed to have maintenance of volume of the reconstructed breast. Her BREAST-Q scores were markedly improved compared with before fat grafting, and there was observable improvement in shape, contour, and symmetry on 2D clinical photography. The 2 new techniques, RoFA mastectomy and large-volume single-stage autologous fat grafting, were used in combination to achieve a satisfactory postmastectomy breast reconstruction. Novel tools for measurement of outcome were the 3D whole-body laser scanner and BREAST-Q questionnaire. This case demonstrates the potential for the use of fat grafting for reconstruction. Outcomes in a larger patient populations are needed to confirm these findings. |
format | Online Article Text |
id | pubmed-4174150 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-41741502014-10-06 Autologous Fat Grafting for Whole Breast Reconstruction Howes, Benjamin H. L. Fosh, Beverley Watson, David I. Yip, Jia Miin Eaton, Michael Smallman, Andrea Dean, Nicola R. Plast Reconstr Surg Glob Open Case Reports SUMMARY: This is the first reported case of a patient who had a single-stage large-volume breast reconstruction with autologous fat grafting, following rotation flap approach (RoFA) mastectomy. The purpose of this case study was to evaluate the viability of reconstruction of the breast by autologous fat grafting alone, in the context of RoFA mastectomy. The hypothesis was that there would be minimal interval loss of autologous fat on the whole breast reconstruction side. Right RoFA mastectomy was used for resection of an invasive primary breast cancer and resulted in the right breast skin envelope. Eleven months later, the patient underwent grafting of 400 ml of autologous fat into the skin envelope and underlying pectoralis major muscle. Outcome was assessed by using a validated 3D laser scan technique for quantitative breast volume measurement. Other outcome measures included the BREAST-Q questionnaire and 2D clinical photography. At 12-month follow-up, the patient was observed to have maintenance of volume of the reconstructed breast. Her BREAST-Q scores were markedly improved compared with before fat grafting, and there was observable improvement in shape, contour, and symmetry on 2D clinical photography. The 2 new techniques, RoFA mastectomy and large-volume single-stage autologous fat grafting, were used in combination to achieve a satisfactory postmastectomy breast reconstruction. Novel tools for measurement of outcome were the 3D whole-body laser scanner and BREAST-Q questionnaire. This case demonstrates the potential for the use of fat grafting for reconstruction. Outcomes in a larger patient populations are needed to confirm these findings. Wolters Kluwer Health 2014-04-07 /pmc/articles/PMC4174150/ /pubmed/25289318 http://dx.doi.org/10.1097/GOX.0000000000000075 Text en Copyright © 2013 The Authors. Published by Lippincott Williams & Wilkins on behalf of The American Society of Plastic Surgeons. PRS Global Open is a publication of the American Society of Plastic Surgeons. http://creativecommons.org/licenses/by-nc-nd/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivitives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. |
spellingShingle | Case Reports Howes, Benjamin H. L. Fosh, Beverley Watson, David I. Yip, Jia Miin Eaton, Michael Smallman, Andrea Dean, Nicola R. Autologous Fat Grafting for Whole Breast Reconstruction |
title | Autologous Fat Grafting for Whole Breast Reconstruction |
title_full | Autologous Fat Grafting for Whole Breast Reconstruction |
title_fullStr | Autologous Fat Grafting for Whole Breast Reconstruction |
title_full_unstemmed | Autologous Fat Grafting for Whole Breast Reconstruction |
title_short | Autologous Fat Grafting for Whole Breast Reconstruction |
title_sort | autologous fat grafting for whole breast reconstruction |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174150/ https://www.ncbi.nlm.nih.gov/pubmed/25289318 http://dx.doi.org/10.1097/GOX.0000000000000075 |
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