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Overexpressed HIF-2α in Endothelial Cells Promotes Vascularization and Improves Random Pattern Skin Flap Survival

BACKGROUND: The local skin flap procedure is very useful for reconstruction. However, flap necrosis caused by circulatory failure can occur at its distal portion. Hypoxia-inducible factors (HIFs) in endothelial cells (ECs) help to maintain ECs and promote vascularization, and HIF-2α is abundantly ex...

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Detalles Bibliográficos
Autores principales:	Morimoto, Atsushi, Tomita, Shuhei, Imanishi, Masaki, Shioi, Go, Kihira, Yoshitaka, Izawa-Ishizawa, Yuki, Takaku, Mitsuru, Hashimoto, Ichiro, Ikeda, Yasumasa, Nakanishi, Hideki, Tamaki, Toshiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2014
Materias:	Experimentals
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174206/ https://www.ncbi.nlm.nih.gov/pubmed/25289325 http://dx.doi.org/10.1097/GOX.0000000000000083

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