Untreatable Surgical Site Infection: Consider Pyoderma Gangrenosum

SUMMARY: Pyoderma gangrenosum (PG) is an inflammatory disease characterized by sterile infiltration of the skin by neutrophils. We describe a case of a 63-year-old woman who developed PG following an abdominal wall reconstruction. Her initial presentation was thought to be consistent with a surgical...

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Detalles Bibliográficos
Autores principales: Berlinrut, Ilan, Bhatia, Nitasha, Josse, Jonathan M., de Vinck, David, Kaul, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2014
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174238/
https://www.ncbi.nlm.nih.gov/pubmed/25289359
http://dx.doi.org/10.1097/GOX.0000000000000114
Descripción
Sumario:SUMMARY: Pyoderma gangrenosum (PG) is an inflammatory disease characterized by sterile infiltration of the skin by neutrophils. We describe a case of a 63-year-old woman who developed PG following an abdominal wall reconstruction. Her initial presentation was thought to be consistent with a surgical site infection. Antibiotic therapy was initiated, and the patient was taken for multiple irrigation/lavage of her abdomen and debridement of necrotic tissue. Wound cultures remained negative, and maximal antibiotic coverage did not halt tissue breakdown. A trial of steroids was initiated, and the patient’s condition subsequently improved. Tissue biopsy results were compatible with the diagnosis of PG.

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